Ignaki - A collection of cartoons about food, computers, art; translated into English. By Ignacio Lafferriere.
The Imp - A humor strip about hell, by Jose Arroyo and Robin Reed.
In Real Life - Following the adventures of Mario, Mega Man, and Link when they are sucked out of the Super NES.
In the Bleachers - Steve Moore's syndicated humor cartoon about sports.
In the Dark - Demons and Angels. Where the battle to free Demonkind from the Netherworld is about to break out. By Alex.
In The Puddle - Semi-reality webcomic by Cique Johnson, about bisexual, lesbian and straight young adults in Philadelphia - starring artist and pastafarian Cique, her guy, and pet bat.
Inepto.com - Lampoons ineptitude at all levels of society, from customer service to CEOs and politicians.
The Infirm - Humor comic about a first-year associate attorney.
Inktank.com - Two strips: Angst Technology, about a game development company, and Weak-end Warriors, about paintball.
Innies and Outties - Funny comic strip about two latchkey kids imagining their way through the enchanted land of suburbia. By Leonard Cachola.
Intelligent Humor - Offbeat comic, also known as "Big Meaty Chunks", by Chris Williams. Collected by Steven Dengler of Xenon Labs.
Interns - Features three interns as they work at a prominent comic book publisher. Includes character bios.
Intershadows - Features an archive of the title, a gallery of sketches and illustrations, and the series Coolville. By Kathleen Jacques.